CONCOMITANT USE OF VENETOCLAX 100 MG AND KETOCONAZOLE TO TREAT CLL IN A PUBLIC CENTER IN BRAZIL
Introduction: Venetoclax has demonstrated substantial efficacy in the treatment of chronic lymphocytic leukemia (CLL). However, the metabolism of venetoclax primarily relies on the cytochrome P450 enzyme CYP3A4, which can be influenced by concurrent administration of strong CYP3A4 inhibitors (ex: ke...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-10-01
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| Series: | Hematology, Transfusion and Cell Therapy |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2531137923005618 |