Pan-cancer evaluation of clinical value of mitotic network activity index (MNAI) and its predictive value for immunotherapy

Pan-cancer evaluation of clinical value of mitotic network activity index (MNAI) and its predictive value for immunotherapy

Increased mitotic activity is associated with the genesis and aggressiveness of many cancers. To assess the clinical value of mitotic activity as prognostic biomarker, we performed a pan-cancer study on the mitotic network activity index (MNAI) constructed based on 54-gene mitotic apparatus network....

Full description

Bibliographic Details
Main Authors: Xuanyu Mao, Yimeng Cai, Sarah Long, Jesus Perez-Losada, Jian-Hua Mao, Hang Chang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Oncology
Subjects:
pan-cancer
breast cancer
mitotic network activity index
prognostic biomarker
genetic instability
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1178568/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1178568/full

Similar Items