Mitochondria dysfunction and metabolic reprogramming as drivers of idiopathic pulmonary fibrosis

Mitochondria dysfunction and metabolic reprogramming as drivers of idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease of unknown etiology. It is characterized by deposition of extracellular matrix proteins, like collagen and fibronectin in the lung interstitium leading to respiratory failure. Our understanding of the pathobiology underlying IPF is st...

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Bibliographic Details
Main Authors: Marta Bueno, Jazmin Calyeca, Mauricio Rojas, Ana L. Mora
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Redox Biology
Subjects:
Fibrosis
Aging
Mitochondrial dysfunction
Epithelial cells
Fibroblast
Macrophage
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720301786

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http://www.sciencedirect.com/science/article/pii/S2213231720301786

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