Endostatin binds biglycan and LDL and interferes with LDL retention to the subendothelial matrix during atherosclerosis

Retention of lipoproteins to proteoglycans in the subendothelial matrix (SEM) is an early event in atherosclerosis. We recently reported that collagen XVIII and its proteolytically released fragment endostatin (ES) are differentially depleted in blood vessels affected by atherosclerosis. Loss of col...

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Bibliographic Details
Main Authors: Xiaokun Zeng, Joshua Chen, Yury I. Miller, Kashi Javaherian, Karen S. Moulton
Format: Article
Language:English
Published: Elsevier 2005-09-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752032931X