pYtags enable spatiotemporal measurements of receptor tyrosine kinase signaling in living cells

pYtags enable spatiotemporal measurements of receptor tyrosine kinase signaling in living cells

Receptor tyrosine kinases (RTKs) are major signaling hubs in metazoans, playing crucial roles in cell proliferation, migration, and differentiation. However, few tools are available to measure the activity of a specific RTK in individual living cells. Here, we present pYtags, a modular approach for...

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Bibliographic Details
Main Authors: Payam E Farahani, Xiaoyu Yang, Emily V Mesev, Kaylan A Fomby, Ellen H Brumbaugh-Reed, Caleb J Bashor, Celeste M Nelson, Jared E Toettcher
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-05-01
Series:eLife
Subjects:
cell signaling
receptor tyrosine kinase
map kinase
biosensor
signaling dynamics
tyrosine phosphorylation
Online Access:https://elifesciences.org/articles/82863

Internet

https://elifesciences.org/articles/82863

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