Trends in use of composite endpoints in clinical trials: A comparison between acute heart failure trials and COVID-19 trials
Composite endpoints can encode multiple pieces of information and are increasingly adopted in clinical trials. Advocacy for using composite endpoints began decades ago in cardiovascular trials, leading to incorporation of patient-oriented outcomes and consideration of a hierarchical ranking system....
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Cambridge University Press
2024-01-01
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Series: | Journal of Clinical and Translational Science |
Subjects: | |
Online Access: | https://www.cambridge.org/core/product/identifier/S2059866124004928/type/journal_article |