Trends in use of composite endpoints in clinical trials: A comparison between acute heart failure trials and COVID-19 trials

Composite endpoints can encode multiple pieces of information and are increasingly adopted in clinical trials. Advocacy for using composite endpoints began decades ago in cardiovascular trials, leading to incorporation of patient-oriented outcomes and consideration of a hierarchical ranking system....

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Bibliographic Details
Main Authors: Lan Shi, Christopher John Lindsell, Dandan Liu
Format: Article
Language:English
Published: Cambridge University Press 2024-01-01
Series:Journal of Clinical and Translational Science
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S2059866124004928/type/journal_article