An immune indicator based on BTK and DPEP2 identifies hot and cold tumors and clinical treatment outcomes in lung adenocarcinoma

Abstract In lung adenocarcinoma (LUAD), immune heterogeneity of hot and cold tumors has been recognized as one of the major factors affecting immunotherapy and other common treatments. However, there is still a lack of biomarkers that can effectively identify the immunophenotype of cold and hot tumo...

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Bibliographic Details
Main Authors: Tao Han, Yafeng Liu, Jing Wu, Ying Bai, Jiawei Zhou, Chunxiao Hu, Wenting Zhang, Jianqiang Guo, Qingsen Wang, Dong Hu
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-32276-2