Peptidoglycan precursor synthesis along the sidewall of pole-growing mycobacteria

Peptidoglycan precursor synthesis along the sidewall of pole-growing mycobacteria

Rod-shaped mycobacteria expand from their poles, yet d-amino acid probes label cell wall peptidoglycan in this genus at both the poles and sidewall. We sought to clarify the metabolic fates of these probes. Monopeptide incorporation was decreased by antibiotics that block peptidoglycan synthesis or...

Full description

Bibliographic Details
Main Authors: Alam García-Heredia, Amol Arunrao Pohane, Emily S Melzer, Caleb R Carr, Taylor J Fiolek, Sarah R Rundell, Hoong Chuin Lim, Jeffrey C Wagner, Yasu S Morita, Benjamin M Swarts, M Sloan Siegrist
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-09-01
Series:eLife
Subjects:
mycobacterium tuberculosis
peptidoglycan
cell wall
metabolic labeling
d-amino acid
mycomembrane
Online Access:https://elifesciences.org/articles/37243

Internet

https://elifesciences.org/articles/37243

Similar Items