Multinucleated Giant Cells Induced by a Silk Fibroin Construct Express Proinflammatory Agents: An Immunohistological Study

Multinucleated Giant Cells Induced by a Silk Fibroin Construct Express Proinflammatory Agents: An Immunohistological Study

Multinucleated giant cells (MNGCs) are frequently observed in the implantation areas of different biomaterials. The main aim of the present study was to analyze the long-term polarization pattern of the pro- and anti-inflammatory phenotypes of macrophages and MNGCs for 180 days to better understand...

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Bibliographic Details
Main Authors: Sarah Al-Maawi, Xuejiu Wang, Robert Sader, Werner Götz, Antonella Motta, Claudio Migliaresi, Charles James Kirkpatrick, Shahram Ghanaati
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Materials
Subjects:
silk fibroin
multinucleated giant cells
inflammation
disintegration
cellular response
Online Access:https://www.mdpi.com/1996-1944/14/14/4038

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https://www.mdpi.com/1996-1944/14/14/4038

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