Results of haploidentical transplant in patients with donor-specific antibodies: a survey on behalf of the Spanish Group of Hematopoietic Transplant and Cell Therapy

Results of haploidentical transplant in patients with donor-specific antibodies: a survey on behalf of the Spanish Group of Hematopoietic Transplant and Cell Therapy

BackgroundDonor-specific antibodies (DSAs) are IgG allo-antibodies against mismatched donor HLA molecules and can cause graft failure (GF) in the setting of haploidentical hematopoietic stem cell transplantation (haplo-HSCT). Our aim was to report the experience of the Spanish Group of Hematopoietic...

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Main Authors: Rebeca Bailén, Raquel Alenda, Beatriz Herruzo-Delgado, Cynthia Acosta-Fleitas, Ana Vallés, Albert Esquirol, Marta Fonseca, Laura Solán, Irene Sánchez-Vadillo, Guiomar Bautista, Leyre Bento, Oriana López-Godino, Ariadna Pérez-Martínez, Anna Torrent, Joud Zanabili, María Calbacho, Miguel Ángel Moreno, María Jesús Pascual-Cascón, Luisa Guerra-Domínguez, Anabelle Chinea, Irene García-Cadenas, Lucía López-Corral, Francisco Boix-Giner, José Luis López Lorenzo, Karem Humala, Rafael Duarte, Antonia Sampol, Inmaculada Heras, José Luis Vicario, Antonio Balas, Gillen Oarbeascoa, Paula Fernández-Caldas, Javier Anguita, Mi Kwon
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
donor-specific antibodies
graft failure
haplo-HSCT
desensitization strategies
DSA kinetics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1165759/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1165759/full

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