Genotoxicity and acute and subchronic toxicity studies of a bioactive polyoxometalate in Wistar rats

Genotoxicity and acute and subchronic toxicity studies of a bioactive polyoxometalate in Wistar rats

Abstract Background Cs2K4Na [SiW9Nb3O40] (POM93) is a novel broad-spectrum antiviral agent with high activity, high stability, and low toxicity in vitro. Most toxicity studies for POM93 have been performed in cultured cell lines rather than in animals. Like other POMs, there is a lack of evidence fo...

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Bibliographic Details
Main Authors: Xiaofeng Qu, Kun Xu, Chao Zhao, Xiuling Song, Jinhua Li, Li Li, Wei Nie, Hao Bao, Juan Wang, Fenglan Niu, Juan Li
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Pharmacology and Toxicology
Subjects:
Polyoxometalate
Acute oral toxicity
Subchronic oral toxicity
Genotoxicity
Online Access:http://link.springer.com/article/10.1186/s40360-017-0133-x

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http://link.springer.com/article/10.1186/s40360-017-0133-x

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