Decoding the physical principles of two-component biomolecular phase separation

Decoding the physical principles of two-component biomolecular phase separation

Cells possess a multiplicity of non-membrane-bound compartments, which form via liquid-liquid phase separation. These condensates assemble and dissolve as needed to enable central cellular functions. One important class of condensates is those composed of two associating polymer species that form on...

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Bibliographic Details
Main Authors: Yaojun Zhang, Bin Xu, Benjamin G Weiner, Yigal Meir, Ned S Wingreen
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-03-01
Series:eLife
Subjects:
phase separation
biomolecular condensates
associative polymers
molecular dynamics simulations
Online Access:https://elifesciences.org/articles/62403

Internet

https://elifesciences.org/articles/62403

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