Synaptic dysfunction of Aldh1a1 neurons in the ventral tegmental area causes impulsive behaviors

Synaptic dysfunction of Aldh1a1 neurons in the ventral tegmental area causes impulsive behaviors

Abstract Background Aldh1a1 neurons are a subtype of gamma-aminobutyric acid (GABA) inhibitory neurons that use Aldh1a1 rather than glutamate decarboxylase (GAD) as an enzyme for synthesizing GABA transmitters. However, the behaviors and circuits of this newly identified subtype of inhibitory intern...

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Bibliographic Details
Main Authors: Xinyan Li, Wenting Chen, Xian Huang, Wei Jing, Tongmei Zhang, Quntao Yu, Hongyan Yu, Hao Li, Qing Tian, Yumei Ding, Youming Lu
Format: Article
Language:English
Published: BMC 2021-10-01
Series:Molecular Neurodegeneration
Subjects:
Aldh1a1 neurons
Synaptic circuits
Delay of gratification
Impulsive behaviors
Alzheimer’s disease
Online Access:https://doi.org/10.1186/s13024-021-00494-9

Internet

https://doi.org/10.1186/s13024-021-00494-9

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