Multi-Scale Spatial Analysis of the Tumor Microenvironment Reveals Features of Cabozantinib and Nivolumab Efficacy in Hepatocellular Carcinoma

Multi-Scale Spatial Analysis of the Tumor Microenvironment Reveals Features of Cabozantinib and Nivolumab Efficacy in Hepatocellular Carcinoma

BackgroundConcomitant inhibition of vascular endothelial growth factor (VEGF) and programmed cell death protein 1 (PD-1) or its ligand PD-L1 is a standard of care for patients with advanced hepatocellular carcinoma (HCC), but only a minority of patients respond, and responses are usually transient....

Full description

Bibliographic Details
Main Authors: Haoyang Mi, Won Jin Ho, Mark Yarchoan, Aleksander S. Popel
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
tumor-immune microenvironments (TIME)
hepatocellular carcinoma
immunotherapy
biomarker
computational biology
systems biology
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.892250/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.892250/full

Similar Items