Catalytic asymmetric oxa-Diels–Alder reaction of acroleins with simple alkenes

Abstract The catalytic asymmetric inverse-electron-demand oxa-Diels–Alder (IODA) reaction is a highly effective synthetic method for creating enantioenriched six-membered oxygen-containing heterocycles. Despite significant effort in this area, simple α,β-unsaturated aldehydes/ketones and nonpolarize...

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Bibliographic Details
Main Authors: Lei Zeng, Shihan Liu, Yu Lan, Lizhu Gao
Format: Article
Language:English
Published: Nature Portfolio 2023-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-39184-z