Poly (ADP-Ribose) and α-synuclein extracellular vesicles in patients with Parkinson disease: A possible biomarker of disease severity.

<h4>Background/objective</h4>Despite multiple attempts, no surrogate biomarker of Parkinson disease (PD) has been definitively identified. Alternatively, identifying a non-invasive biomarker is crucial to understanding the natural history, severity, and progression of PD and to guide fut...

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Main Authors: Fabrice Lucien, Eduardo E Benarroch, Aidan Mullan, Farwa Ali, Bradley F Boeve, Michelle M Mielke, Ronald C Petersen, Yohan Kim, Cole Stang, Emanuele Camerucci, Owen A Ross, Zbigniew K Wszolek, David Knopman, James Bower, Wolfgang Singer, Rodolfo Savica
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0264446