Comprehensive data-driven analysis of the impact of chemoinformatic structure on the genome-wide biological response profiles of cancer cells to 1159 drugs

<p>Abstract</p> <p>Background</p> <p>Detailed and systematic understanding of the biological effects of millions of available compounds on living cells is a significant challenge. As most compounds impact multiple targets and pathways, traditional methods for analyzing...

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Bibliographic Details
Main Authors: Khan Suleiman A, Faisal Ali, Mpindi John, Parkkinen Juuso A, Kalliokoski Tuomo, Poso Antti, Kallioniemi Olli P, Wennerberg Krister, Kaski Samuel
Format: Article
Language:English
Published: BMC 2012-05-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/13/112