Apoptotic exosome-like vesicles transfer specific and functional mRNAs to endothelial cells by phosphatidylserine-dependent macropinocytosis

Apoptotic exosome-like vesicles transfer specific and functional mRNAs to endothelial cells by phosphatidylserine-dependent macropinocytosis

Abstract Apoptosis of endothelial cells prompts the release of apoptotic exosome-like vesicles (ApoExos), subtype extracellular vesicles secreted by apoptotic cells after caspase-3 activation. ApoExos are different from both apoptotic bodies and classical exosomes in their protein and nucleic acid c...

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Main Authors: Alexandre Brodeur, Francis Migneault, Maude Lanoie, Déborah Beillevaire, Julie Turgeon, Annie Karakeussian-Rimbaud, Nicolas Thibodeau, Éric Boilard, Mélanie Dieudé, Marie-Josée Hébert
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05991-x

Internet

https://doi.org/10.1038/s41419-023-05991-x

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