Uptake of severe acute respiratory syndrome coronavirus 2 spike protein mediated by angiotensin converting enzyme 2 and ganglioside in human cerebrovascular cells

Uptake of severe acute respiratory syndrome coronavirus 2 spike protein mediated by angiotensin converting enzyme 2 and ganglioside in human cerebrovascular cells

IntroductionThere is clinical evidence of neurological manifestations in coronavirus disease-19 (COVID-19). However, it is unclear whether differences in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)/spike protein (SP) uptake by cells of the cerebrovasculature contribute to significan...

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Bibliographic Details
Main Authors: Conor McQuaid, Alexander Solorzano, Ian Dickerson, Rashid Deane
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Neuroscience
Subjects:
brain endothelial cells
brain pericytes
brain vascular smooth muscle cells
COVID-19
SARS-CoV-2 variants of interest and lipid raft
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1117845/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2023.1117845/full

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