Reduced mitochondrial DNA content correlate with poor clinical outcomes in cryotransfers with day 6 single euploid embryos

Reduced mitochondrial DNA content correlate with poor clinical outcomes in cryotransfers with day 6 single euploid embryos

ObjectiveTo investigate whether the mitochondrial DNA (mtDNA) content of a single biopsy at trophoblast correlates with the developmental potential and reproductive outcomes of blastocyst.MethodsA retrospective analysis applied the dataset of 1,675 embryos with preimplantation genetic testing for an...

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Bibliographic Details
Main Authors: Tzu-Hsuan Chuang, Chih-Yen Chen, Chin-Sheng Kuan, Hsing-Hua Lai, Chia-Lin Hsieh, Meng-Ju Lee, Yi-Ting Liang, Yu-Jen Chang, Chien-Yu Chen, Shee-Uan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Endocrinology
Subjects:
mitochondria
blastocyst formation day
preimplantation genetic testing for aneuploidy(PGT-A)
next-generation sequencing
single embryo transfer (SET)
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1066530/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.1066530/full

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