Modeling the Altered Expression Levels of Genes on Signaling Pathways in Tumors as Causal Bayesian Networks

This paper concerns a study indicating that the expression levels of genes in signaling pathways can be modeled using a causal Bayesian network (BN) that is altered in tumorous tissue. These results open up promising areas of future research that can help identify driver genes and therapeutic target...

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Bibliographic Details
Main Authors: Richard Neapolitan, Diyang Xue, Xia Jiang
Format: Article
Language:English
Published: SAGE Publishing 2014-01-01
Series:Cancer Informatics
Online Access:https://doi.org/10.4137/CIN.S13578