MAVE-NN: learning genotype-phenotype maps from multiplex assays of variant effect
Abstract Multiplex assays of variant effect (MAVEs) are a family of methods that includes deep mutational scanning experiments on proteins and massively parallel reporter assays on gene regulatory sequences. Despite their increasing popularity, a general strategy for inferring quantitative models of...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2022-04-01
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| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-022-02661-7 |