The essential roles of m6A RNA modification to stimulate ENO1-dependent glycolysis and tumorigenesis in lung adenocarcinoma

The essential roles of m6A RNA modification to stimulate ENO1-dependent glycolysis and tumorigenesis in lung adenocarcinoma

Abstract Background Lung adenocarcinoma (LUAD)  is the most common subtype of lung cancer. Patient prognosis is poor, and the existing therapeutic strategies for LUAD are far from satisfactory. Recently, targeting N6-methyladenosine (m6A) modification of RNA has been suggested as a potential strateg...

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Bibliographic Details
Main Authors: Lifang Ma, Xiangfei Xue, Xiao Zhang, Keke Yu, Xin Xu, Xiaoting Tian, Yayou Miao, Fanyu Meng, Xiaoxin Liu, Susu Guo, Shiyu Qiu, Yikun Wang, Jiangtao Cui, Wanxin Guo, You Li, Jinjing Xia, Yongchun Yu, Jiayi Wang
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
METTL3
ALKBH5
YTHDF1
translation
lung cancer
RNA-protein interaction
Online Access:https://doi.org/10.1186/s13046-021-02200-5

Internet

https://doi.org/10.1186/s13046-021-02200-5

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