Therapeutic Benefit of the Association of Lodenafil with Mesenchymal Stem Cells on Hypoxia-induced Pulmonary Hypertension in Rats

Therapeutic Benefit of the Association of Lodenafil with Mesenchymal Stem Cells on Hypoxia-induced Pulmonary Hypertension in Rats

Pulmonary arterial hypertension (PAH) is characterized by the remodeling of pulmonary arteries, with an increased pulmonary arterial pressure and right ventricle (RV) overload. This work investigated the benefit of the association of human umbilical cord mesenchymal stem cells (hMSCs) with lodenafil...

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Bibliographic Details
Main Authors: Marina de Moraes Carvalho da Silva, Allan Kardec Nogueira de Alencar, Jaqueline Soares da Silva, Tadeu Lima Montagnoli, Grazielle Fernandes da Silva, Bruna de Souza Rocha, Guilherme Carneiro Montes, Rosália Mendez-Otero, Pedro Moreno Pimentel-Coelho, Juliana F. Vasques, Margarete Manhães Trahez, Roberto Takashi Sudo, Gisele Zapata-Sudo
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
pulmonary arterial hypertension
PDE5 inhibitor
human mesenchymal stem cells
association therapy
Online Access:https://www.mdpi.com/2073-4409/9/9/2120

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https://www.mdpi.com/2073-4409/9/9/2120

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