Engineered extracellular vesicles derived from primary M2 macrophages with anti-inflammatory and neuroprotective properties for the treatment of spinal cord injury

Engineered extracellular vesicles derived from primary M2 macrophages with anti-inflammatory and neuroprotective properties for the treatment of spinal cord injury

Abstract Background Uncontrollable inflammation and nerve cell apoptosis are the most destructive pathological response after spinal cord injury (SCI). So, inflammation suppression combined with neuroprotection is one of the most promising strategies to treat SCI. Engineered extracellular vesicles w...

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Bibliographic Details
Main Authors: Chuanjie Zhang, Daoyong Li, Hengshuo Hu, Zhe Wang, Jinyu An, Zhanshan Gao, Kaihua Zhang, Xifan Mei, Chao Wu, He Tian
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Journal of Nanobiotechnology
Subjects:
Spinal cord injury
Extracellular vesicles
Curcumin
M2 repolarization
Neuroprotection
Online Access:https://doi.org/10.1186/s12951-021-01123-9

Internet

https://doi.org/10.1186/s12951-021-01123-9

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