Cell morphology and mechanosensing can be decoupled in fibrous microenvironments and identified using artificial neural networks

Abstract Cells interpret cues from and interact with fibrous microenvironments through the body based on the mechanics and organization of these environments and the phenotypic state of the cell. This in turn regulates mechanoactive pathways, such as the localization of mechanosensitive factors. Her...

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Detalles Bibliográficos
Autores principales: Edward D. Bonnevie, Beth G. Ashinsky, Bassil Dekky, Susan W. Volk, Harvey E. Smith, Robert L. Mauck
Formato: Artículo
Lenguaje:English
Publicado: Nature Portfolio 2021-03-01
Colección:Scientific Reports
Acceso en línea:https://doi.org/10.1038/s41598-021-85276-5