ECDEP: identifying essential proteins based on evolutionary community discovery and subcellular localization

Abstract Background In cellular activities, essential proteins play a vital role and are instrumental in comprehending fundamental biological necessities and identifying pathogenic genes. Current deep learning approaches for predicting essential proteins underutilize the potential of gene expression...

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Bibliographic Details
Main Authors: Chen Ye, Qi Wu, Shuxia Chen, Xuemei Zhang, Wenwen Xu, Yunzhi Wu, Youhua Zhang, Yi Yue
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-024-10019-5