ECDEP: identifying essential proteins based on evolutionary community discovery and subcellular localization

ECDEP: identifying essential proteins based on evolutionary community discovery and subcellular localization

Abstract Background In cellular activities, essential proteins play a vital role and are instrumental in comprehending fundamental biological necessities and identifying pathogenic genes. Current deep learning approaches for predicting essential proteins underutilize the potential of gene expression...

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Podrobná bibliografie
Hlavní autoři: Chen Ye, Qi Wu, Shuxia Chen, Xuemei Zhang, Wenwen Xu, Yunzhi Wu, Youhua Zhang, Yi Yue
Médium: Článek
Jazyk:English
Vydáno: BMC 2024-01-01
Edice:BMC Genomics
Témata:
Essential protein
Evolutionary community discovery
Protein–protein interaction network
Subcellular localization
Gene expression
On-line přístup:https://doi.org/10.1186/s12864-024-10019-5

Internet

https://doi.org/10.1186/s12864-024-10019-5

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