Genetic basis of hindlimb loss in a naturally occurring vertebrate model

Genetic basis of hindlimb loss in a naturally occurring vertebrate model

Here we genetically characterise pelvic finless, a naturally occurring model of hindlimb loss in zebrafish that lacks pelvic fin structures, which are homologous to tetrapod hindlimbs, but displays no other abnormalities. Using a hybrid positional cloning and next generation sequencing approach, we...

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Bibliographic Details
Main Authors: Emily K. Don, Tanya A. de Jong-Curtain, Karen Doggett, Thomas E. Hall, Benjamin Heng, Andrew P. Badrock, Claire Winnick, Garth A. Nicholson, Gilles J. Guillemin, Peter D. Currie, Daniel Hesselson, Joan K. Heath, Nicholas J. Cole
Format: Article
Language:English
Published: The Company of Biologists 2016-03-01
Series:Biology Open
Subjects:
Pelvic fin
Development
TALENs
Hindlimb
Tbx4
Online Access:http://bio.biologists.org/content/5/3/359

Internet

http://bio.biologists.org/content/5/3/359

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