Inhibition of Glycogen Synthase Kinase 3β Activity in the Basolateral Amygdala Disrupts Reconsolidation and Attenuates Heroin Relapse

Inhibition of Glycogen Synthase Kinase 3β Activity in the Basolateral Amygdala Disrupts Reconsolidation and Attenuates Heroin Relapse

Exposure to a heroin-associated conditioned stimulus can reactivate drug reward memory, trigger drug cravings, and induce relapse in heroin addicts. The amygdala, a brain region related to emotions and motivation, is involved in processing rewarding stimulus. Recent evidence demonstrated that disrup...

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Bibliographic Details
Main Authors: Yuanyang Xie, Yingfan Zhang, Ting Hu, Zijin Zhao, Qing Liu, Haoyu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
addiction
heroin
amygdala
reconsolidation
GSK-3β
self-administration
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.932939/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.932939/full

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