The natural history of molecular functions inferred from an extensive phylogenomic analysis of gene ontology data.

The origin and natural history of molecular functions hold the key to the emergence of cellular organization and modern biochemistry. Here we use a genomic census of Gene Ontology (GO) terms to reconstruct phylogenies at the three highest (1, 2 and 3) and the lowest (terminal) levels of the hierarch...

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Bibliographic Details
Main Authors: Ibrahim Koç, Gustavo Caetano-Anollés
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5414959?pdf=render