Long read sequencing reveals poxvirus evolution through rapid homogenization of gene arrays
Poxvirus adaptation can involve combinations of recombination-driven gene copy number variation and beneficial single nucleotide variants (SNVs) at the same loci. How these distinct mechanisms of genetic diversification might simultaneously facilitate adaptation to host immune defenses is unknown. W...
Main Authors: | Thomas A Sasani, Kelsey R Cone, Aaron R Quinlan, Nels C Elde |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-08-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/35453 |
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