The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner

<p>Abstract</p> <p>Background</p> <p>CTCF is a highly conserved and essential zinc finger protein expressed in virtually all cell types. In conjunction with cohesin, it organizes chromatin into loops, thereby regulating gene expression and epigenetic events. The functio...

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Bibliographic Details
Main Authors: Sleutels Frank, Soochit Widia, Bartkuhn Marek, Heath Helen, Dienstbach Sven, Bergmaier Philipp, Franke Vedran, Rosa-Garrido Manuel, van de Nobelen Suzanne, Caesar Lisa, van der Reijden Michael, Bryne Jan, van IJcken Wilfred, Grootegoed J, Delgado M, Lenhard Boris, Renkawitz Rainer, Grosveld Frank, Galjart Niels
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Epigenetics & Chromatin
Subjects:
Online Access:http://www.epigeneticsandchromatin.com/content/5/1/8