SARS-CoV-2 causes secretory diarrhea with an enterotoxin-like mechanism, which is reduced by diosmectite

Background and aims: The pathophysiology of SARS-CoV-2-associated diarrhea is unknown. Using an experimental model validated for rotavirus-induced diarrhea, we investigated the effects of SARS-CoV-2 on transepithelial ion fluxes and epithelial integrity of human intestinal cells. The effect of the a...

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Bibliographic Details
Main Authors: Marco Poeta, Valentina Cioffi, Vittoria Buccigrossi, Francesco Corcione, Roberto Peltrini, Angela Amoresano, Fabio Magurano, Maurizio Viscardi, Giovanna Fusco, Antonietta Tarallo, Carla Damiano, Andrea Lo Vecchio, Eugenia Bruzzese, Alfredo Guarino
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Heliyon
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Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022015341