Bidirectional two-sample Mendelian randomization analysis reveals a causal effect of interleukin-18 levels on postherpetic neuralgia risk

Bidirectional two-sample Mendelian randomization analysis reveals a causal effect of interleukin-18 levels on postherpetic neuralgia risk

BackgroundPostherpetic neuralgia (PHN) is a debilitating complication of herpes zoster, characterized by persistent neuropathic pain that significantly impairs patients’ quality of life. Identifying factors that determine PHN susceptibility is crucial for its management. Interleukin-18 (IL-18), a pr...

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Bibliographic Details
Main Authors: Xiao Liang, Yuchao Fan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
postherpetic neuralgia
interleukin-18
bidirectional Mendelian randomization
genome-wide association study
herpes zoster
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1183378/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1183378/full

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