The Envelope Cytoplasmic Tail of HIV-1 Subtype C Contributes to Poor Replication Capacity through Low Viral Infectivity and Cell-to-Cell Transmission.

The Envelope Cytoplasmic Tail of HIV-1 Subtype C Contributes to Poor Replication Capacity through Low Viral Infectivity and Cell-to-Cell Transmission.

The cytoplasmic tail (gp41CT) of the HIV-1 envelope (Env) mediates Env incorporation into virions and regulates Env intracellular trafficking. Little is known about the functional impact of variability in this domain. To address this issue, we compared the replication of recombinant virus pairs carr...

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Bibliographic Details
Main Authors: Eveline Santos da Silva, Martin Mulinge, Morgane Lemaire, Cécile Masquelier, Cyprien Beraud, Arkadiusz Rybicki, Jean-Yves Servais, Gilles Iserentant, Jean-Claude Schmit, Carole Seguin-Devaux, Danielle Perez Bercoff
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5012655?pdf=render

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http://europepmc.org/articles/PMC5012655?pdf=render

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