Protein C or Protein S deficiency associates with paradoxically impaired platelet‐dependent thrombus and fibrin formation under flow

Protein C or Protein S deficiency associates with paradoxically impaired platelet‐dependent thrombus and fibrin formation under flow

Abstract Background Low plasma levels of protein C or protein S are associated with venous thromboembolism rather than myocardial infarction. The high coagulant activity in patients with thrombophilia with a (familial) defect in protein C or S is explained by defective protein C activation, involvin...

Full description

Bibliographic Details
Main Authors: Sanne L. N. Brouns, Bibian M. E. Tullemans, Cristiana Bulato, Gina Perrella, Elena Campello, Luca Spiezia, Johanna P. vanGeffen, Marijke J. E. Kuijpers, René vanOerle, Henri M. H. Spronk, Paola E. J. van derMeijden, Paolo Simioni, Johan W. M. Heemskerk
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
anticoagulation
coagulation
fibrin
platelet
thrombin
thrombophilia
Online Access:https://doi.org/10.1002/rth2.12678

Internet

https://doi.org/10.1002/rth2.12678

Similar Items