Episodic positive selection in the evolution of avian toll-like receptor innate immunity genes.

Toll-like receptors (TLRs) are a family of conserved pattern-recognition molecules responsible for initiating innate and acquired immune responses. Because they play a key role in host defence, these genes have received increasing interest in the evolutionary and population genetics literature, as t...

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Bibliographic Details
Main Authors: Catherine E Grueber, Graham P Wallis, Ian G Jamieson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3940441?pdf=render