CHAF1A promotes the proliferation and growth of epithelial ovarian cancer cells by affecting the phosphorylation of JAK2/STAT3 signaling pathway

CHAF1A promotes the proliferation and growth of epithelial ovarian cancer cells by affecting the phosphorylation of JAK2/STAT3 signaling pathway

The molecular mechanism of chromatin assembly factor 1 unit A (CHAF1A) promoting the proliferation and growth of epithelial ovarian cancer (EOC) cells hasn’t been reported at present. In this study, recombinant CHAF1A siRNA/overexpression plasmid (si-RNA1/pcDNA3.1-CHAF1A) was designed and constructe...

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Bibliographic Details
Main Authors: Dandan Xia, Xun Xu, Jing Wei, Wenli Wang, Jiali Xiong, Qingqing Tan, Pingping Xue, Huiyan Wang
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Biochemistry and Biophysics Reports
Subjects:
【Key words】CHAF1A
Epithelial ovarian cancer
JAK2
STAT3
Proliferation
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580823001036

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http://www.sciencedirect.com/science/article/pii/S2405580823001036

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