Development of aptamer based colorimetric assay for whole blood glycated hemoglobin (HbA1c) estimation using gold nanoparticles

Development of aptamer based colorimetric assay for whole blood glycated hemoglobin (HbA1c) estimation using gold nanoparticles

Thiol-modified aptamer oligonucleotides containing gold nanoparticles (G@NPs) bound to glycated hemoglobin (HbA1c) with high affinity in whole blood samples. Aptamer thiol groups enhanced the stability of aptamers adsorbed on the surface of G@NPs. A detection strategy was used to visually confirm th...

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Bibliographic Details
Main Authors: Rooma Devi, Aman Chauhan, Sandeep Yadav, Prabhat Kumar, C.S. Pundir
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Biosensors and Bioelectronics: X
Subjects:
Glycated hemoglobin
Aptamer
Gold nanoparticles
Colorimetric detection
Whole blood
Online Access:http://www.sciencedirect.com/science/article/pii/S2590137023000018

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http://www.sciencedirect.com/science/article/pii/S2590137023000018

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