Indirectly recognized HLA-C mismatches and their potential role in transplant outcome

Indirectly recognized HLA-C mismatches and their potential role in transplant outcome

HLA-C mismatches are clearly associated to alloreactivity after hematopoietic stem-cell transplantation; in a number of large cohorts, HLA-C mismatches are correlated to an increased risk of acute graft-versus-host disease (GVHD) or even impaired survival. While for HLA-A and -B both antigenic as we...

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Bibliographic Details
Main Authors: Kirsten Anne Thus, Liane ete Boome, Juergen eKuball, Eric eSpierings
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Immunology
Subjects:
Epitopes, T-Lymphocyte
Transplantation Immunology
GvHD
HLA
HSCT
indirect recognition
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00210/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00210/full

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