Downregulation of Ribosomal Protein Genes Is Revealed in a Model of Rat Hippocampal Neuronal Culture Activation with GABA(A)R/GlyRa2 Antagonist Picrotoxin

Downregulation of Ribosomal Protein Genes Is Revealed in a Model of Rat Hippocampal Neuronal Culture Activation with GABA(A)R/GlyRa2 Antagonist Picrotoxin

Long-read transcriptome sequencing provides us with a convenient tool for the thorough study of biological processes such as neuronal plasticity. Here, we aimed to perform transcriptional profiling of rat hippocampal primary neuron cultures after stimulation with picrotoxin (PTX) to further understa...

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Bibliographic Details
Main Authors: Alexander Beletskiy, Anastasia Zolotar, Polina Fortygina, Ekaterina Chesnokova, Leonid Uroshlev, Pavel Balaban, Peter Kolosov
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cells
Subjects:
long-read sequencing
ONT MinION
RNA-Seq
primary neuronal cultures
neuronal plasticity
picrotoxin
Online Access:https://www.mdpi.com/2073-4409/13/5/383

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https://www.mdpi.com/2073-4409/13/5/383

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