Characterizing the hard and soft nanoparticle-protein corona with multilayer adsorption

Characterizing the hard and soft nanoparticle-protein corona with multilayer adsorption

Nanoparticles (NPs) in contact with biological fluid adsorb biomolecules into a corona. This corona comprises proteins that strongly bind to the NP (hard corona) and loosely bound proteins (soft corona) that dynamically exchange with the surrounding solution. While the kinetics of hard corona format...

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Bibliographic Details
Main Authors: Oriol Vilanova, Alberto Martinez-Serra, Marco P. Monopoli, Giancarlo Franzese
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Nanotechnology
Subjects:
biomolecular corona
protein adsorption kinetics
protein-nanoparticle interactions
coarse-grain modeling
molecular simulations
transferrin
Online Access:https://www.frontiersin.org/articles/10.3389/fnano.2024.1531039/full

Internet

https://www.frontiersin.org/articles/10.3389/fnano.2024.1531039/full

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