<i>miR-31</i>-<i>NUMB</i> Cascade Modulates Monocarboxylate Transporters to Increase Oncogenicity and Lactate Production of Oral Carcinoma Cells

<i>miR-31</i>-<i>NUMB</i> Cascade Modulates Monocarboxylate Transporters to Increase Oncogenicity and Lactate Production of Oral Carcinoma Cells

Oral squamous cell carcinoma (OSCC) is among the leading causes of cancer-associated death worldwide. <i>miR-31</i> is an oncogenic miRNA in OSCC. NUMB is an adaptor protein capable of suppressing malignant transformation. Disruption of the <i>miR-31</i>-<i>NUMB</i&g...

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Bibliographic Details
Main Authors: Chung-Hsien Chou, Chun-Yu Fan Chiang, Cheng-Chieh Yang, Ying-Chieh Liu, Sih-Rou Chang, Kuo-Wei Chang, Shu-Chun Lin
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
CRISPR
lactate
<i>MCT1</i>
<i>MCT4</i>
<i>miR-31</i>
<i>NUMB</i>
Online Access:https://www.mdpi.com/1422-0067/22/21/11731

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https://www.mdpi.com/1422-0067/22/21/11731

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