Exploring Novel Variants of the Cytochrome P450 Reductase Gene (<i>POR</i>) from the Genome Aggregation Database by Integrating Bioinformatic Tools and Functional Assays
Cytochrome P450 oxidoreductase (POR) is an essential redox partner for steroid and drug-metabolizing cytochromes P450 located in the endoplasmic reticulum. Mutations in <i>POR</i> lead to metabolic disorders, including congenital adrenal hyperplasia, and affect the metabolism of steroids...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-11-01
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| Series: | Biomolecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2218-273X/13/12/1728 |