In HCMV-exposed HUVEC, P52/RelB regulatory factors mediate activation of the human PAR1 gene promoter

We studied the effect of HCMV (AD-169) on the regulation of PAR1 reporter activity in HUVEC. In HUVEC, HCMV significantly induced activation of PAR1 reporter constructs carrying AP-2-like and two complexes of AP-2/Sp1-binding elements. Shorter constructs with no AP-2-like binding elements had lower...

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Bibliographic Details
Main Authors: Popović M., Paskaš Svetlana, Živković Maja, Đurić-Delić Tamara, Stanković Aleksandra, Burysek L.
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2009-01-01
Series:Archives of Biological Sciences
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2009/0354-46640904613P.pdf