Production and characterisation of a neutralising chimeric antibody against botulinum neurotoxin A.

Botulinum neurotoxins, produced by Clostridium botulinum bacteria, are the causative agent of botulism. This disease only affects a few hundred people each year, thus ranking it among the orphan diseases. However, botulinum toxin type A (BoNT/A) is the most potent toxin known to man. Due to their po...

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Bibliographic Details
Main Authors: Julie Prigent, Christelle Mazuet, Didier Boquet, Patricia Lamourette, Hervé Volland, Michel R Popoff, Christophe Créminon, Stéphanie Simon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2953832?pdf=render