Human cytomegalovirus UL138 interaction with USP1 activates STAT1 in infection.

Innate immune responses are crucial for limiting virus infection. However, viruses often hijack our best defenses for viral objectives. Human Cytomegalovirus (HCMV) is a beta herpesvirus which establishes a life-long latent infection. Defining the virus-host interactions controlling latency and reac...

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Bibliographic Details
Main Authors: Kristen Zarrella, Pierce Longmire, Sebastian Zeltzer, Donna Collins-McMillen, Meaghan Hancock, Jason Buehler, Justin M Reitsma, Scott S Terhune, Jay A Nelson, Felicia Goodrum
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011185