Predicting weighted unobserved nodes in a regulatory network using answer set programming

Abstract Background The impact of a perturbation, over-expression, or repression of a key node on an organism, can be modelled based on a regulatory and/or metabolic network. Integration of these two networks could improve our global understanding of biological mechanisms triggered by a perturbation...

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Bibliographic Details
Main Authors: Sophie Le Bars, Mathieu Bolteau, Jérémie Bourdon, Carito Guziolowski
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-023-05429-3