Proteomic and genomic analyses of antimony resistant Leishmania infantum mutant.

Antimonials remain the primary antileishmanial drugs in most developing countries. However, drug resistance to these compounds is increasing and our understanding of resistance mechanisms is partial.In the present study, quantitative proteomics using stable isotope labelling of amino acids in cell c...

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Bibliographic Details
Main Authors: Marie-Christine Brotherton, Sylvie Bourassa, Philippe Leprohon, Danielle Légaré, Guy G Poirier, Arnaud Droit, Marc Ouellette
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3842243?pdf=render